深圳欣博盛生物科技有限公司 a1

AZD-7762 hydrochloride
货号:SYN-1017-M001 规格:1 mg 目录价:¥1204
货号:SYN-1017-M005 规格:5 mg 目录价:¥1512
货号:SYN-1017-M010 规格:10 mg 目录价:¥2422
货号:SYN-1017-M050 规格:50 mg 目录价:¥7406
货号:SYN-1017-M100 规格:100 mg 目录价:¥询价
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AZD-7762 hydrochloride
别名:
AZD7762
产品描述:
Checkpoint kinases CHK1 and CHK2 are activated in response to DNA damage that results in cell cycle arrest, allowing sufficient time for DNA repair. Agents that lead to abrogation of such checkpoints have potential to increase the efficacy of such compounds as chemo- and radiotherapies. AZD7762 is a specific inhibitor for the CHK1/2 kinases with IC(50) values less than 10. AZD7762 enhances radiation sensitivity and gemcitabine-mediated radiosensitization in pancreatic cancer cells and xenografts and thus is helpful in the treatments of potentially many cancers. In addition, AZD7762 is a chemosensitizer and with gemcitabine and radiation produced a significant delay in the growth of pancreatic tumor xenografts with tolerable toxicity. AZD7762 is being studied as an important link in improving both adjuvant therapy and the treatment of metastatic disease.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
362.4 . 36.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
860352-01-8
分子式:
C17H19FN4O2S . HCl
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询