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折扣/货期| 货号：79-908 | 规格：0.1 mg | 目录价：￥6598.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E2A (phospho Thr355) Antibody
别名:
E12, Tran, TCF3, TFE2, ITF1
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
IHC
靶标/特异性:
The antibody detects endogenous levels of E2A only when phosphorylated at threonine 355.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
Store antibody at -20˚C for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产地:
美国
生产商:
Prosci
功能与背景:
E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Accession #:
NP_003191.1
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