深圳欣博盛生物科技有限公司 a1

LY2801653
货号:25978-1 mg 规格:1 mg 目录价:¥924.6
货号:25978-10 mg 规格:10 mg 目录价:¥4864.2
货号:25978-5 mg 规格:5 mg 目录价:¥2653.2
货号:25978-50 mg 规格:50 mg 目录价:¥13172.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LY2801653
别名:
Merestinib
产品描述:
A MET kinase inhibitor (Ki = 2 nM); inhibits MST1R, Axl, MNK1/2, FLT3, DDR1, and DDR2 (IC50s = 11, 2, 7, 7, 0.1, and 7 nM, respectively); inhibits HGF-induced MET autophosphorylation in H460 and S114 cells (IC50s = 35.2 and 59.2 nM, respectively) and inhibits growth of Ba/F3 cells transfected with MET-activating mutations (IC50s = 12-248 nM); completely blocks cell scattering induced by HGF in DU145 cells at 0.01-10 µM; reduces tumor growth in MET autocrine (U-87MG) and MET over-expression (H441) mouse xenograft models at 4 and 12 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
552.531126
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1206799-15-6
分子式:
C30H22F2N6O3
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