PECAM-1 (phospho Tyr713) Antibody-多抗-深圳欣博盛生物科技有限公司

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PECAM-1 (phospho Tyr713) Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：80-043

规格：0.1 mg

目录价：￥6598.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PECAM-1 (phospho Tyr713) Antibody

别名:

CD31, CD31 antigen, EndoCAM, PEC1, PECAM

反应种属:

Human,Mouse

宿主来源:

Rabbit

实验应用:

靶标/特异性:

The antibody detects endogenous level of PECAM-1 only when phosphorylated at tyrosine 713.

同种型:

IgG

克隆性:

Polyclonal

纯化方式:

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

偶联:

Unconjugated

产品浓度:

1 mg/mL

保存温度:

Store antibody at -20˚C for up to one year.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

产地:

美国

生产商:

Prosci

功能与背景:

Induces susceptibility to atherosclerosis By similarity. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte.

Accession #:

NP_000433.4

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