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anti-PD-1 (mouse), mAb (blocking) (1H10)
品牌： Adipogen
产品货号： AG-20B-0075-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-PD-1 (mouse), mAb (blocking) (1H10)
  • 别名:
    CD279; Programmed Cell Death Protein 1
  • 产品描述:
    CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signaling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.
  • 反应种属:
  • 宿主来源:
    Purified from concentrated hybridoma tissue culture supernatant.
  • 实验应用:
    FACS, FUNC (Blocking)
  • 靶标/特异性:
  • 同种型:
    Rat IgG2akappa
  • 推荐稀释度:
  • 免疫原:
    Mouse PD-1 transfected cell line.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    1H10
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 0.02% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 0.02% sodium azide.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
    <0.01EU/µg purified protein (LAL test; Lonza).
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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