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产品名称:
anti-Apaf-1, mAb (18H2)
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别名:
Apoptosis Protease-activating Factor 1
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产品描述:
Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome, mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.
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反应种属:
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宿主来源:
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实验应用:
ELISA, ICC, IP, WB
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靶标/特异性:
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同种型:
Rat IgG2akappa
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推荐稀释度:
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免疫原:
Recombinant mouse Apaf-1 (aa 1-97) containing the N-terminal CARD domain.
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免疫原种属:
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克隆性:
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克隆号:
18H2
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纯化方式:
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偶联:
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产品浓度:
1mg/ml
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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外观:
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生产商:
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功能与背景:
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
Liquid. In PBS containing 0.02% sodium azide.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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来源:
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表达方式:
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Accession #:
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CAS号:
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分子式:
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溶解度:
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PubChem CID: