您好，欢迎光临欣博盛生物科技商城！
服务热线：400 680 0892
购物车图片 购物车 ( )
anti-TLR6 (human), mAb (ABM1B50)
品牌： Adipogen
产品货号： AG-20T-0305-C100
规格： 100 ug

报价：
折后价：

数量： - +
问题咨询
官网链接
说明书
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
  • 产品名称:
    anti-TLR6 (human), mAb (ABM1B50)
  • 别名:
    Toll-like Receptor 6; CD286
  • 产品描述:
    TLR6 (Toll-like Receptor 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 in complex with TLR2 specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides from Gram-positive bacteria and fungi. The activation cluster TLR2:TLR6:CD14:CD36 signals via MYD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. In complex with TLR2 recognizes MALP-2, STF, PSM and OspA-L, as well. In response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42, TLR6 forms a heterodimer with TLR4. This complex rapidly internalizes and triggers inflammatory responses through the NF-kappaB-dependent MYD88 signaling or via TICAM1 signaling pathways. The complex promotes sterile inflammation in monocytes/macrophages. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Various polymorphism have been associated with inflammatory and tumor pathologies.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
    FACS, WB
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1kappa
  • 推荐稀释度:
  • 免疫原:
    Recombinant human TLR6 protein (aa 280-512).
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    ABM1B50
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    0.5mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 6 months after receipt when stored at +4°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
  • 产品特点:
  • 纯度:
    Protein G purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
关注欣博盛公众号
Copyright ©2021 - 2023 深圳欣博盛生物科技有限公司
粤ICP备08007346号
  网站地图
犀牛云提供企业云服务