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anti-TLR9, mAb (ABM1C51) (FITC)
品牌: Adipogen
产品货号: AG-20T-0308F-C100
规格: 100 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    anti-TLR9, mAb (ABM1C51) (FITC)
  • 别名:
    Toll-like Receptor 9; CD289
  • 产品描述:
    TLR9 (Toll-like Receptor 9) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR9 is expressed by numerous cells of the immune system such as B lymphocytes, monocytes, natural killer (NK) cells and plasmacytoid dendritic cells. It is expressed intracellularly, within the endosomal compartments and functions to alert the immune system of viral and bacterial infections by binding to DNA rich in CpG motifs. This nucleotide-sensing TLR is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides (also called oligodinucleotides, ODNs), and consequently signals via MYD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response and eventually activation of a Th1-biased adaptive immune attack. Specific TLR9 agonists have been shown to have substantial antitumor activity, making the TLR9 signaling pathway an interesting target for therapeutic research.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
    FACS
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1kappa
  • 推荐稀释度:
  • 免疫原:
    Recombinant human TLR9 protein (aa 100-290).
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    ABM1C51
  • 纯化方式:
  • 偶联:
    FITC
  • 产品浓度:
    0.2mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    +4°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 10mM TRIS containing 150mM NaCl and 0.05% sodium azide.
  • 有效期:
    Stable for at least 6 months after receipt when stored at +4°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In 10mM TRIS containing 150mM NaCl and 0.05% sodium azide.
  • 产品特点:
  • 纯度:
    Protein G purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
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  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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