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anti-TLR10 (human), mAb (ABM3C85)
品牌： Adipogen
产品货号： AG-20T-0310-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-TLR10 (human), mAb (ABM3C85)
  • 别名:
    Toll-like Receptor 10; CD290
  • 产品描述:
    TLR10 (Toll-like Receptor10) is an orphan member of the TLR family and is the only pattern-recognition receptor without known ligand specificity and biological function. TLR10 is predominantly expressed in tissues rich in immune cells, such as spleen, lymph node, thymus, tonsil, and lung. This protein plays a role in innate immune responses following viral infection. Influenza virus infection increased TLR10 expression and TLR10 contributed to innate immune sensing of viral infection leading to cytokine induction, including proinflammatory cytokines and interferons. Blocking TLR10 by antagonistic antibodies enhanced proinflammatory cytokine production, including IL-1beta specifically after exposure to TLR2 ligands. Like TLR1 and TLR6, TLR10 has also been shown to form a heterodimer complex with TLR2 during Helicobacter pylori infection and that it could be involved in the recognition of FSL-1, LPS and flagellin. TLR10 is an important innate immune sensor of viral infection with a role in innate immune defense and immunopathology following viral and bacterial pathogen infection.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
    WB
  • 靶标/特异性:
  • 同种型:
    Mouse IgG2akappa
  • 推荐稀释度:
  • 免疫原:
    Recombinant human TLR10 protein (aa 100-369).
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    ABM3C85
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    0.5mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 6 months after receipt when stored at +4°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
  • 产品特点:
  • 纯度:
    Protein G purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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