anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) - 深圳欣博盛生物科技有限公司

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anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4)

品牌： Adipogen

产品货号： AG-27B-0015-C100

规格： 100 ug

报价：

折后价：

数量： - +

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产品名称:

anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4)
别名:

Ang-2; Ang2; Angpt2; Agpt2
产品描述:

Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
反应种属:
宿主来源:

Produced without the use of animals. Purified from CHO cell culture supernatant.
实验应用:

ELISA, FUNC (Blocking)
靶标/特异性:
同种型:

Human IgG2lambda.
推荐稀释度:
免疫原:

Recombinant human angiopoietin-2.
免疫原种属:
克隆性:
克隆号:

Angy-1-4
纯化方式:
偶联:
产品浓度:

1mg/ml
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
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URL:
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样本类型:

Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产品特点:
纯度:

>95% (SDS-PAGE)
生物活性:
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