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STAT3 antibody [STAT3/2409]
品牌: GeneTex
产品货号: GTX18120
规格: 100μg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    STAT3 antibody [STAT3/2409]
  • 别名:
    ADMIO , ADMIO1 , APRF , HIES , STAT3 , signal transducer and activator of transcription 3
  • 产品描述:
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    IHC-P, Protein Array
  • 靶标/特异性:
  • 同种型:
    IgG2b
  • 推荐稀释度:
  • 免疫原:
    Recombinant human full-length STAT3 protein
  • 免疫原种属:
  • 克隆性:
    Monoclonal
  • 克隆号:
    STAT3/2409
  • 纯化方式:
    Protein A/G purified
  • 偶联:
    Unconjugated
  • 产品浓度:
    0.2 mg/ml (Please refer to the vial label for the specific concentration.)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
  • 运输温度:
    4°C
  • 细胞定位:
  • 预期分子量:
    88
  • 产品形式:
    Liquid
  • 存储溶液:
    10mM PBS, 0.05% BSA
  • 有效期:
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    10mM PBS, 0.05% BSA
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
  • 来源:
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  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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