IL-8 (human):Fc (human) (rec.) (non-lytic) - 深圳欣博盛生物科技有限公司

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IL-8 (human):Fc (human) (rec.) (non-lytic)

品牌： Adipogen

产品货号： CHI-HF-22008-C050

规格： 50 ug

报价：

折后价：

数量： - +

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产品名称:

IL-8 (human):Fc (human) (rec.) (non-lytic)
别名:

Interleukin-8; CXCL8; C-X-C Motif Chemokine 8; Emoctakin; GCP-1; LAI; MDNCF; MONAP; NAP-1; NCF; TCF
产品描述:

Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro.
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宿主来源:

CHO cells
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保存温度:

-20°C
运输温度:

BLUE ICE
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产品形式:

solid
存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.
有效期:

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:

瑞士
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样本类型:

Lyophilized from 0.2µm-filtered solution in PBS.
产品特点:
纯度:

>98% (SDS-PAGE)
生物活性:

Shows the biological function of the IL-8 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:

<0.06EU/µg protein (LAL test; Lonza).
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