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FGF-23 (mouse):Fc (human) (rec.)
品牌: Adipogen
产品货号: AG-40A-0128Y-C010
规格: 10 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    FGF-23 (mouse):Fc (human) (rec.)
  • 别名:
    Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
  • 产品描述:
    FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
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  • 推荐稀释度:
  • 免疫原:
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  • 产品浓度:
    0.1mg/ml after reconstitution
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~40kDa (SDS-PAGE); full-length FGF23 is cleaved between Arg179 and Ser 180.
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
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  • 检测方法:
  • 样本类型:
    Lyophilized. Contains PBS.
  • 产品特点:
  • 纯度:
    >90% (SDS-PAGE)
  • 生物活性:
    Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.
  • 内毒素水平:
    <0.02EU/µg purified protein (LAL test; Lonza).
  • 来源:
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