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产品名称:
BVR Protein
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别名:
Biliverdin Reductase Protein, Biliverdin IX alpha reductase Protein, Biliverdin reductase A Protein, Biliverdin-IX alpha-reductase Protein, BLVR A Protein, BLVR Protein, Blvra Protein, BVR A Protein, BVRA Protein, Zinc metalloProtein, zinc-metalloprotein Protein
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产品描述:
Rat Natural BVR Full Length Protein
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反应种属:
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宿主来源:
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实验应用:
WB | SDS-PAGE
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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克隆号:
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纯化方式:
Ion-exchange Purified
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偶联:
No tag
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产品浓度:
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表达系统:
Native
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阳性对照:
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保存温度:
-80ºC
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运输温度:
Blue Ice or 4ºC
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细胞定位:
Cytoplasm
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预期分子量:
~36 kDa
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产品形式:
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存储溶液:
10mM Tris pH7.5, 0.1mM EDTA, 0.2mM DTT, 20% glycerol
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有效期:
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产地:
加拿大
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外观:
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生产商:
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功能与背景:
Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH7.0 and NADPH at pH8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
10mM Tris pH7.5, 0.1mM EDTA, 0.2mM DTT, 20% glycerol
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产品特点:
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纯度:
>90%
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生物活性:
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内毒素水平:
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来源:
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表达方式:
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Accession #:
NP_446302.1
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CAS号:
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分子式:
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溶解度:
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PubChem CID: