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Citrullinated α-Enolase (human, recombinant)
品牌： Cayman
产品货号： 21585
规格： 100 µg

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折后价：

数量： - +
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  • 产品名称:
    Citrullinated α-Enolase (human, recombinant)
  • 别名:
    Enolase-1
  • 产品描述:
    α-Enolase, also known as enolase-1, is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.{42086} It is ubiquitously expressed in human tissues, including liver, spleen, kidney, and brain. In cells, α-enolase is primarily localized to the cytoplasm, however, an alternatively translated form localizes to the nucleus and lacks glycolytic enzyme activity.{42086,42087} α-Enolase functions as a cell surface receptor for plasminogen on pathogens and activated immune cells, as an oxidative stress protein in endothelial cells, and as a chromatin binding partner to facilitate transcription.{42087,42088,42089} It is an autoantigen in asthma, Hashimoto's encephalopathy, and rheumatoid arthritis, and has been found in the serum of pediatric patients with juvenile idiopathic arthritis.{42090,42091,42092,36062} α-Enolase is also subject to citrullination by peptidyl arginine deiminases (PADs) and citrullinated α-enolase has been found in the synovial fluid of rheumatoid arthritis patients.{42092}
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  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    TBS, pH 7.4
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥90% estimated by SDS-PAGE
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