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TDO (Anopheles gambiae) (rec.) (His)
品牌： Adipogen
产品货号： AG-40T-0101-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    TDO (Anopheles gambiae) (rec.) (His)
  • 别名:
    TPH2; TRPO; Tryptophan 2,3-dioxygenase; Tryptophan Oxygenase; Tryptophan Pyrrolase; Tryptophanase
  • 产品描述:
    Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin; in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.
  • 反应种属:
  • 宿主来源:
    Synthetic.
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  • 推荐稀释度:
  • 免疫原:
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  • 偶联:
  • 产品浓度:
    0.5mg/ml (Lot specific)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80°C
  • 运输温度:
    DRY ICE
  • 细胞定位:
  • 预期分子量:
    ~47.9kDa
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -80°C.
  • 产地:
    瑞士
  • 外观:
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  • 检测方法:
  • 样本类型:
    Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol.
  • 产品特点:
  • 纯度:
    >98% (SDS-PAGE)
  • 生物活性:
    Specific activity towards L-Trp: 87.0µmol/hr per mg. TDO catalyzes the oxidative opening of the L-tryptophan indole moiety to yield N-formylkynurenine (NFK).
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