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17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1α
品牌： Cayman
产品货号： 15895-1 mg
规格： 1 mg

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数量： - +
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  • 产品名称:
    17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1α
  • 别名:
    17-TFM-PGF1α
  • 产品描述:
    A number of 17-aryl trinor and 16-aryloxy tetranor prostaglandin F2α derivatives have been approved for the treatment of glaucoma.{8941,9341,8839} These “ring” prostaglandin (PG) analogs have improved efficacy over the PGs with an n-alkyl lower side chain. Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.{9736} 17-trifluoromethylphenyl-13,14-dihydro trinor PGF1α (17-TFM-PGF1α) is a typical “ring” analog reminiscent of the trifluoromethyl-phenoxy ring of Travoprost. The a chain of 17-TFM-PGF1α is saturated, making this compound a formal member of the one-series PGs. Recent work has shown that in the “ring” series of analogs, this modification has little impact on FP receptor binding.{9668} As an ocular hypotensive agent, it is expected that 17-TFM-PGF1α would act very much like the free acid of latanoprost.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    460.5
  • 产品形式:
    A solution in methyl acetate
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • CAS号:
    1027401-98-4
  • 分子式:
    C24H35F3O5
  • 溶解度:
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