产品描述:
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.{8342,8343} Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. It is often used in combination with a progestin to induce estrus in domestic livestock.{13000} Estradiol benzoate binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM.{12991} This reflects a 6-10 fold reduction in binding affinity compared to estradiol.{12991}