产品描述:
Elaidic Acid-d17 is intended for use as an internal standard for the quantification of elaidic acid (Item No. 90250) by GC- or LC-MS. Elaidic acid is a monounsaturated trans fatty acid and the 9-trans isomer of oleic acid (Item Nos. 90260 | 24659) that has been found in partially hydrogenated cooking oils.{2046} It reduces HHT and HETE formation and increases synthesis of prostaglandin E2 (PGE2; Item No. 14010), PGF2α (Item Nos. 16010 | 16020), PGD2 (Item No. 12010), and thromboxane B2 (TXB2; Item No. 19030) induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) in isolated human platelets. Elaidic acid (0.1-5 mmol/L) induces apoptosis in human umbilical vein endothelial cells (HUVECs).{57088} In vivo, elaidic acid (100 mg/kg) reduces cardiac and hepatic autophagy induced by palmitic acid (Item No. 10006627) in mice.{57089}