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产品名称:
Auranofin
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别名:
1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate; NSC 321521; SKF 39162; Triethylphosphine gold
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产品描述:
Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway. Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5. Potent thioredoxin reductase (TrxR) inhibitor. Induces mitochondrial membrane permeability transition. Anti-cancer compound with anti-proliferative activity. Shown to induce apoptosis and necrosis. STAT3 and telomerase activity inhibitor. Proteasomal deubiquitinase inhibitor. Antibiotic, antiviral and antiparasitic compound. Immunosuppressive.
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阳性对照:
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保存温度:
-20°C
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运输温度:
Ambient
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细胞定位:
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预期分子量:
678.5
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产品形式:
solid
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存储溶液:
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有效期:
Stable for at least 2 years after receipt when stored at +20°C.
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产地:
瑞士
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纯度:
>95%
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Accession #:
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CAS号:
34031-32-8
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分子式:
C20H34AuO9PS
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溶解度:
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PubChem CID: