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产品名称:
Fluticasone propionate
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别名:
Fluticasone 17-Propionate; (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester; CCI 18781
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产品描述:
Fluticasone propionate is a synthetic corticosteroid. It is a high affinity, selective glucocorticoid receptor agonist (Kd = 0.5nM). It is used as an anti-inflammatory agent for asthma. It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis and other airway diseases. It potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis in vitro. It also potentiates KV1 channels (EC50 = 37nM).
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反应种属:
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宿主来源:
Synthetic
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实验应用:
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靶标/特异性:
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同种型:
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推荐稀释度:
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偶联:
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产品浓度:
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表达系统:
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阳性对照:
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保存温度:
+20°C
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运输温度:
Ambient
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细胞定位:
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预期分子量:
500.57
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产品形式:
solid
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存储溶液:
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有效期:
Stable for at least 2 years after receipt when stored at RT.
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产地:
瑞士
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外观:
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功能与背景:
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URL:
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灵敏度:
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产品特点:
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纯度:
>97% (NMR)
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生物活性:
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内毒素水平:
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来源:
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表达方式:
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Accession #:
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CAS号:
80474-14-2
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分子式:
C25H31F3O5S
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溶解度:
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PubChem CID: