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产品名称:
STAT6 peptide
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别名:
signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C
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产品描述:
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反应种属:
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宿主来源:
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实验应用:
IP
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靶标/特异性:
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同种型:
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克隆性:
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克隆号:
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纯化方式:
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偶联:
Unconjugated
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产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
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表达系统:
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阳性对照:
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保存温度:
Store this product at 4ºC, DO NOT FREEZE. The product is stable for one year from the date of shipment.
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运输温度:
4°C
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细胞定位:
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预期分子量:
94
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产品形式:
Liquid
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存储溶液:
PBS, BSA
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有效期:
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产地:
美国
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外观:
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生产商:
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功能与背景:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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URL:
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检测方法:
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样本类型:
PBS, BSA
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