产品描述:
5'-pGpG is a linearized form of cyclic di-GMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).{24607, 50984, 28201} It is a metabolite of cyclic di-GMP (Item No. 17144) formed via hydrolysis by various phosphodiesterases (PDEs) that binds to the cyclic di-GMP-I riboswitch with reduced affinity compared to cyclic di-GMP.{28201,54908} 5'-pGpG is intended for use as a negative control for cyclic di-GMP signaling.