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PAMAM Dendrimer G5.0 Amine (water solution)
品牌: Cayman
产品货号: 39075
规格: 500 mg

报价:
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数量: - +
产品详情
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  • 产品名称:
    PAMAM Dendrimer G5.0 Amine (water solution)
  • 别名:
    PAMAM G5.0|Polyamidoamine Dendrimer G5.0
  • 产品描述:
    PAMAM dendrimer G5.0 amine (PAMAM G5.0) is a polyamidoamine (PAMAM) dendrimer with amine termini.{51536} It is approximately 54 Å in diameter and has 128 surface groups. PAMAM G5.0 (10 µg/ml) reduces viability, induces cell cycle arrest at the sub-G1/M phase, and increases lactate dehydrogenase (LDH) release from RAW 264.7 macrophages.{68596} It also induces DNA fragmentation in the same cells when used at a concentration of 15 µg/ml. PAMAM G5.0 in complex with siRNA targeting Pou5f1 mRNA, the gene encoding Oct4, reduces Oct4 expression in mouse embryonic stem cells.{68597} Intravenous administration of PAMAM G5.0 in complex with reporter gene DNA increases reporter gene expression in the lung, spleen, and liver, but not the heart, in mice.{68598} Conjugates of PAMAM G5.0 with the contrast agent gadolinium increases small vessel contrast quality compared to conjugates of gadolinium with the cell-impermeable metal chelating agent diethylenetriaminepentaacetic acid (DTPA; Item No. 33307).{68599}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    28824.8
  • 产品形式:
    A solution in water
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • CAS号:
    163442-68-0
  • 分子式:
    [NH2(CH2)2NH2]:(G=5);dendri PAMAM(NH2)128
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