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PAMAM Dendrimer G3.0 Amidoethanol (water solution)
品牌: Cayman
产品货号: 39112-1 g
规格: 1 g

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    PAMAM Dendrimer G3.0 Amidoethanol (water solution)
  • 别名:
    PAMAM 3.0 Amidoethanol|Polyamidoamine Dendrimer G3.0 Amidoethanol
  • 产品描述:
    PAMAM dendrimer G3.0 amidoethanol (PAMAM G3.0 amidoethanol) is a polyamidoamine (PAMAM) dendrimer with hydroxyl termini.{67576} It is approximately 30 Å in diameter in PBS and has 32 surface groups. PAMAM G3.0 amidoethanol is an antagonist for the pore-forming channels anthrax protective antigen 63 (PA63) in lipid membranes (IC50 = 44.9 nM).{67569} It inhibits aggregation of amylin containing a serine-to-glycine substitution at position 20 (amylinS20G) in a concentration-dependent manner and amylinS20G-induced toxicity in MIN6-K8 and NIT-1 pancreatic β-cells at 6 µM.{65920} Topical application of PAMAM G3.0 amidoethanol (1 mg/ml) encapsulating the synthetic glucocorticoid dexamethasone (Item No. 11015) increases the levels of dexamethasone in the sclera, conjunctiva, and cornea in isolated rabbit eyes.{65921} It reduces tail growth in C. riparius larvae and induces DNA damage in a comet assay using C. riparius larval homogenates when used at concentrations of 10 or 100 ppm.{65922}
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    6940.4
  • 产品形式:
    A solution in water
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 分子式:
    [NH2(CH2)2NH2]:(G=3);dendri PAMAM(NHCH2CH2OH)32
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