产品描述:
VH 032 linker 1 is a precursor in the synthesis of the proteolysis-targeting chimeras (PROTACs) that contain a terminal amine conjugated via a PEG linker to VHL ligand 1 (Item No. 21591), which binds to VHL E3 ligase. It has been used in the synthesis of PROTACs targeting TEA domain transcription factors (TEADs) in cancer cells.{68635}