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折扣/货期| 货号：14-988 | 规格：100 uL | 目录价：￥7651.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
RAD18 Antibody
别名:
RAD18, RNF73
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
WB,IHC,IF
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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