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折扣/货期| 货号：CDX-V0013-M025 | 规格：25 mg | 目录价：￥1876 |
| 货号：CDX-V0013-M050 | 规格：50 mg | 目录价：￥4620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Vinblastine sulfate salt
别名:
VLB; Vincaleukoblastine sulfate salt; NSC 49842
产品描述:
Vinblastine sulfate is a vinca alkaloid and a chemical analog of vincristine. It is an anticancer agent with anti-mitotic properties and immunosuppressive activity. Vinblastine sulfate depolymerizes microtubules by binding tubulin and inducing self-association in spiral aggregates. This reaction that appears to be regulated by the C-terminus of beta-tubulin and is enhanced by GDP and GTP. Vinblastine sulfate has been observed to arrest the cell cycle in the G2/M-phase by blocking mitotic spindle formation. Vinblastine sulfate has also been documented to trigger Raf-1 activation and phosphorylation of Bcl-2 family proteins, to induce p53 expression, and to induce apoptosis in several tumor cell lines. Shown to inhibit autophagosome maturation.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
909.05
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
143-67-9
分子式:
C46H58N4O9 . H2SO4
溶解度:
Soluble in DMSO (10mg/ml), DMF (10mg/ml) or water (10mg/ml).
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