| 货号:12720-1 mg | 规格:1 mg | 目录价:¥2331.6 |
| 货号:12720-100 µg | 规格:100 µg | 目录价:¥522.6 |
| 货号:12720-500 µg | 规格:500 µg | 目录价:¥1299.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
15(R)-15-methyl Prostaglandin D2
别名:
15(R)-15-methyl PGD2
产品描述:
The physiological actions of PGD2 include regulation of sleep, lowering of body temperature, inhibition of platelet aggregation and relaxation of vascular smooth muscle.{328,1185,580} PGD2 mediates its effects by 2 distinct G-protein-coupled receptors, DP1{3128} and CRTH2/DP2.{10722,9769} 15(R)-15-methyl PGD2 is a potent, selective agonist for the CRTH2/DP2 receptor.{10723} The EC50 values for eosinophil CD11b expression, actin polymerization, and chemotaxis are 1.4, 3.8, and 1.7 nM, respectively, each of which is approximately 3-5 fold lower than those for PGD2. In contrast the EC50 for the DP1-mediated increase in platelet cAMP by 15(R)-15-methyl PGD2 is >10 µM.{10723}
保存温度:
-20
运输温度:
-20
预期分子量:
366.5
产品形式:
A 1 mg/ml solution in methyl acetate
有效期:
1460
纯度:
≥95%
CAS号:
210978-26-0
分子式:
C21H34O5
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