| 货号:19288-1 mg | 规格:1 mg | 目录价:¥523 |
| 货号:19288-10 mg | 规格:10 mg | 目录价:¥3095 |
| 货号:19288-25 mg | 规格:25 mg | 目录价:¥6459 |
| 货号:19288-5 mg | 规格:5 mg | 目录价:¥1688 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
(1S,3R)-RSL3
产品描述:
A ferroptosis inducer; inhibits GPX4 in a context-dependent manner; inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3ε but does not inhibit recombinant human selenocysteine-containing GPX4 or purified rat testis GPX4, at 100 µM; inhibits peroxidase activity in GPX4-overexpressing COH-BR1 breast cancer cell lysates at 50 nM; inhibits TrxR1 (IC50 = 7.9 µM in a cell-free assay); selectively cytotoxic to H-RasV12-expressing BJeLR cells over wild-type Ras-expressing BJeH cells (EC50s = 0.01 and 2 µM, respectively); induces lipid peroxidation in Pfa1 fibroblasts at 100 nM; prevents tumor formation and inhibits tumor growth in BJeLR mouse xenograft models at 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
440.9
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1219810-16-8
分子式:
C23H21ClN2O5
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