深圳欣博盛生物科技有限公司 a1

4-Methylhistamine (hydrochloride)
货号:23761-1 mg 规格:1 mg 目录价:¥482
货号:23761-10 mg 规格:10 mg 目录价:¥2935
货号:23761-5 mg 规格:5 mg 目录价:¥1715
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
4-Methylhistamine (hydrochloride)
产品描述:
A histamine H4 receptor agonist (Ki = 50 nM); >100-fold selective for H4 over other histamine receptors; inhibits forskolin-induced CRE-β-galactosidase activity in SK-N-MC cells transfected with the human H4 receptor (EC50 = 39.8 nM); induces a change in eosinophil shape (EC50 = 0.36 μM) and stimulates migration of murine bone marrow mast cells (EC50 = 12 μM); reduces airway resistance and inflammation and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of allergic asthma when administered intratracheally at a dose of 10 μg/animal; reduces epidermal hyperplasis, hyperkeratosis, and lymphocyte infiltration and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of imiquimod-induced psoriasis
保存温度:
-20
运输温度:
-20
预期分子量:
125.18
产品形式:
A solid
纯度:
≥95%
CAS号:
36376-47-3
分子式:
C6H11N3 • 2HCl
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