5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione-抑制剂-深圳欣博盛生物科技有限公司

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5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-P0110-M005	规格：5 mg	目录价：￥1386
货号：CDX-P0110-M010	规格：10 mg	目录价：￥2212
货号：CDX-P0110-M050	规格：50 mg	目录价：￥8834

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione

别名:

(Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione; SMI-16a

产品描述:

Potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively) as well as DYRK1alpha (68% inhibition of DYRK1alpha and Pim-2 at 5 µM), while exhibiting little or no activity against a panel of 57 other kinases (<18% inhibition at 5 µM). Reported to exhibit antitumor activity in PC3 human prostate cancer cultures in vitro (IC50 = 48 µM) and in JC adenocarcinoma-transplanted Balb/C mice in vivo (~46% tumor mass reduction on day 20| 50 mg/kg via daily i.p.).

宿主来源:

Synthetic

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

263.3

产品形式:

solid

产地:

瑞士