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折扣/货期| 货号：CDX-A0306-M001 | 规格：1 mg | 目录价：￥1106 |
| 货号：CDX-A0306-M005 | 规格：5 mg | 目录价：￥2212 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
6-Amino-D-luciferin
别名:
4,5-Dihydro-2[6-amino-2-benzthiazolyl]-4-thiazole carboxylic acid
产品描述:
Amino analog of the common D-luciferin substrate for use in measuring firefly luciferase activity. This cell permeable reagent can be used when considering design of proluminescent bioconjugates (peptidase substrates) of luciferin for ultrasensitive luminescent assays. In bioluminescent protease assays peptides or amino acids are conjugated to the luciferin analog 6-amino-D-luciferin. These substrates are useful for ultrasensitive analysis of a variety of protease enzymes including various caspases and cathepsins, chymotrypsin, trypsin, elastase, kallikrein, thrombin, ficin, bromoalain, plasmin, papain, ficin and many others or even for use in vivo tracing of luciferase transfected cells in living tissues. The resulting bioluminescence spectrum of reaction of 6-Amino-D-luciferin is very similar to that observed for the natural substrate D-luciferin. Peptidase assays using a bioluminogenic substrate can be easily adapted to 96-well formats for HTS-based assays. Using this principle, it is possible to design an assay to detect almost any peptidase or protease activity via bioluminescence by using a substrate with a suitable peptide sequence. Applications in pathogen detection, discovery of protease inhibitors, probing cell physiology and assessing protease activity in oncogenesis are possible at extraordinary sensitivity.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
279.34
产品形式:
solid
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
161055-47-6
分子式:
C11H9N3O2S2
促销活动
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