深圳欣博盛生物科技有限公司 a1

6-OHDA (hydrobromide)
货号:25330-1 g 规格:1 g 目录价:¥6901
货号:25330-250 mg 规格:250 mg 目录价:¥2157
货号:25330-50 mg 规格:50 mg 目录价:¥576
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
6-OHDA (hydrobromide)
别名:
2,4,5-Trihydroxyphenethylamine|6-hydroxy Dopamine|Oxidopamine
产品描述:
A catecholaminergic neurotoxin; has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinson's disease in rodents; induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, MFB, or striatum at doses of 9, 6, and 18 μg, respectively; decreases dopamine and norepinephrine levels in rat brain at 200 μg; induces apoptosis in primary rat cortical cells and PC12 rat adrenal cells at 50 μM; activates caspase-3, -8, and -9 in a time-dependent manner and increases the level of intracellular ROS in PC12 cells at 75 μM; induces apoptosis in rat substantia nigra when stereotaxically injected into the right MFB
保存温度:
-20
运输温度:
-20
预期分子量:
169.17788
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
636-00-0
分子式:
C8H11NO3 • HBr
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