6(5H)-Phenanthridinone-抑制剂-深圳欣博盛生物科技有限公司

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6(5H)-Phenanthridinone

品牌：Cayman

官网链接

说明书

折扣/货期

货号：28730-1 mg	规格：1 mg	目录价：￥536
货号：28730-10 mg	规格：10 mg	目录价：￥3296
货号：28730-25 mg	规格：25 mg	目录价：￥7517
货号：28730-5 mg	规格：5 mg	目录价：￥1769

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

6(5H)-Phenanthridinone

别名:

NSC 11021|NSC 40943|NSC 61083

产品描述:

An inhibitor of PARP1 and 2 (EC50s = 10.2 and 36.3 μM, respectively, in yeast cells expressing the human enzymes); decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells at 50 μM; reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes; reduces spinal cord expression of iNOS, IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of EAE at 60 mg/kg; decreases serum levels of lactate dehydrogenase as well as hepatic lipid peroxidation, oxidative DNA damage, and PARP levels in a mouse model of carbon tetrachloride-induced hepatotoxicity at 10 mg/kg

保存温度:

-20

运输温度:

-20

预期分子量:

195.2167

产品形式:

A solid

纯度:

≥98%

CAS号:

1015-89-0