深圳欣博盛生物科技有限公司 a1

A-419259
货号:25605-1 mg 规格:1 mg 目录价:¥1206
货号:25605-10 mg 规格:10 mg 目录价:¥5253
货号:25605-5 mg 规格:5 mg 目录价:¥2935
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
A-419259
别名:
RK-20449
产品描述:
An inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 μM); inhibits growth of Ph+ K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 μM, respectively), but not Ph- TF-1 and HEL cells; induces apoptosis in K-562 cells in a concentration-dependent manner; inhibits differentiation of murine embryonic stem cells while maintaining pluripotency at 300 nM; reduces the total number of AML cells, as well as AML stem cells, in the bone marrow and spleen of human patient-derived AML mouse xenograft models at 30 mg/kg twice daily
保存温度:
-20
运输温度:
-20
预期分子量:
482.6201
产品形式:
A solid
纯度:
≥98%
CAS号:
364042-47-7
分子式:
C29H34N6O
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