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折扣/货期| 货号：18168-1 mg | 规格：1 mg | 目录价：￥657 |
| 货号：18168-10 mg | 规格：10 mg | 目录价：￥4409 |
| 货号：18168-25 mg | 规格：25 mg | 目录价：￥10211 |
| 货号：18168-5 mg | 规格：5 mg | 目录价：￥2385 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
A-419259 (hydrochloride)
别名:
RK-20449
产品描述:
An inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 μM); inhibits growth of Ph+ K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 μM, respectively), but not Ph- TF-1 and HEL cells; induces apoptosis in K-562 cells in a concentration-dependent manner; inhibits differentiation of murine embryonic stem cells while maintaining pluripotency at 300 nM; reduces the total number of AML cells, as well as AML stem cells, in the bone marrow and spleen of human patient-derived AML mouse xenograft models at 30 mg/kg twice daily
保存温度:
-20
运输温度:
-20
预期分子量:
482.6201
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1435934-25-0
分子式:
C29H34N6O • 3HCl
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