| 货号:42375-10 mg | 规格:10 mg | 目录价:¥2104 |
| 货号:42375-100 mg | 规格:100 mg | 目录价:¥9326 |
| 货号:42375-5 mg | 规格:5 mg | 目录价:¥1166 |
| 货号:42375-50 mg | 规格:50 mg | 目录价:¥6419 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
A-582941
产品描述:
An agonist of a7 nAChRs; induces inward currents in Xenopus oocytes expressing the rat or human receptor (EC50s = 2.45 and 4.26 µM, respectively), which can be reversed by methyllycaconitine; selectively binds to a7 nAChRs (Kis = 10.8 and 16.7 nM for the rat and human receptors, respectively) over a panel of >75 receptors and ion channels, including muscarinic receptors, at 10 µM but does bind to 5-HT3 (Ki = 154 nM); improves cognitive deficits in the 3xTg transgenic mouse model of Alzheimer’s disease at 12 mg/kg; increases accuracy in the DMTS test in rhesus monkeys at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
280.36766
产品形式:
A solid
纯度:
≥98%
CAS号:
848591-90-2
分子式:
C17H20N4 • 2HCl
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