深圳欣博盛生物科技有限公司 a1

A-77636 (hydrochloride)
货号:24316-1 mg 规格:1 mg 目录价:¥656.6
货号:24316-10 mg 规格:10 mg 目录价:¥3470.6
货号:24316-5 mg 规格:5 mg 目录价:¥2385.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
A-77636 (hydrochloride)
产品描述:
An agonist of the dopamine D1 receptor (Ki=40 nM); induces activity equal to or greater than dopamine in fish retinas and rat caudate-putman (EC50s = 7.4 and 1.1 nM, respectively); does not show agonist behavior for the D2 receptor expressed in MMQ cells (≤10 μM); induces desensitization of dopamine-stimulated cAMP accumulation and reduces D1 receptor expression by 79% in C-6 glioma cells expressing monkey D1A receptors (10 μM); increases locomotor activity 5.3-fold and reduces disease severity in a MPTP-treated marmoset model of Parkinson's disease (3 μmol/kg s.c.); elicits over a 230% increase in cortical and hippocampal acetylcholine release (4 μmol/kg, s.c.)
保存温度:
-20
运输温度:
-20
预期分子量:
329.43332
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
145307-34-2
分子式:
C20H27NO3 • HCl
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