| 货号:21810-1 mg | 规格:1 mg | 目录价:¥482 |
| 货号:21810-10 mg | 规格:10 mg | 目录价:¥3591 |
| 货号:21810-25 mg | 规格:25 mg | 目录价:¥7866 |
| 货号:21810-5 mg | 规格:5 mg | 目录价:¥2050 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AAT-008
产品描述:
An orally bioavailable, potent, and selective EP4 receptor antagonist (IC50 = 16.3 nM in a human EP4 functional assay); selective for EP4, with IC50 values of 2.4, 1,890, >20,000, and >20,000 nM for binding to human EP4, EP2, EP1, and EP3, respectively; has potent binding affinity for human, rat, and dog EP4 (Kis = 0.97, 6.1, and 38 nM, respectively; suppresses PGE2-induced elevation of intracellular cAMP in vitro (pA2 = 1.1 nM); reduces carrageenan-induced mechanical hyperalgesia in rats in a dose-dependent manner
保存温度:
-20
运输温度:
-20
预期分子量:
414.8
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
847727-81-5
分子式:
C21H16ClFN2O4
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