ABCB1 Antibody / P Glycoprotein / MDR1-多抗-深圳欣博盛生物科技有限公司

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ABCB1 Antibody / P Glycoprotein / MDR1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RQ6755

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ABCB1 Antibody / P Glycoprotein / MDR1

产品描述:

P-GP, also called ABCB1, MDR1 and PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the bloodï¿½brain barrier.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, IF, FACS

同种型:

Rabbit IgG

免疫原:

Amino acids TKEALDESIPPVSFWRIMK from the human protein were used as the immunogen for the ABCB1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity purified

保存温度:

After reconstitution, the ABCB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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