深圳欣博盛生物科技有限公司 a1

ABT-594 (hydrochloride)
货号:22822-1 mg 规格:1 mg 目录价:¥549
货号:22822-10 mg 规格:10 mg 目录价:¥4181
货号:22822-25 mg 规格:25 mg 目录价:¥9112
货号:22822-5 mg 规格:5 mg 目录价:¥2385
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ABT-594 (hydrochloride)
别名:
Ebanicline|Tebanicline
产品描述:
A potent agonist of neuronal α4β2 subunit-containing nAChRs (Ki = 37 pM in a radioligand binding assay); selective for neuronal nAChRs over neuromuscular α1β1δγ subunit-containing nAChRs (Ki = 10,000 nM), α1B-, α2B-, and α2C-adrenergic receptors (Kis = 890, 597, and 342 nM, respectively), and 70 other receptors, enzymes and transporters (Kis = >1,000 nM) in radioligand binding assays; induces [86Rb+] efflux in K177 cells transfected with human neuronal α4β2 subunit-containing nAChRs (EC50 = 140 nM); increases latency to paw withdrawal in a hot-plate test in rats at 0.05 and 0.01 mg/kg; induces hypothermia, seizures, and an increase in blood pressure in rats
保存温度:
-20
运输温度:
-20
预期分子量:
198.64922
产品形式:
A solid
纯度:
≥95%
CAS号:
203564-54-9
分子式:
C9H11ClN2O • HCl
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