深圳欣博盛生物科技有限公司 a1

ABT-639
货号:28742-1 mg 规格:1 mg 目录价:¥657
货号:28742-10 mg 规格:10 mg 目录价:¥3792
货号:28742-25 mg 规格:25 mg 目录价:¥8643
货号:28742-5 mg 规格:5 mg 目录价:¥2546
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ABT-639
产品描述:
A T-type calcium channel blocker; inhibits inactivated-state Cav3.2 channels (IC50 = 2.3 μM) and inactivated-state Cav3.1 and Cav3.3 channels by 50 and 39%, respectively, at 10 μM; selectively inhibits inactivated-state T-type calcium currents over resting-state currents in rat DRG neurons (IC50s = 7.6 and >30 μM, respectively); reverses the hind limb grip force deficit in a rat model of MIA-induced osteoarthritic pain (ED50 = 2 mg/kg); dose-dependently increases the paw withdrawal threshold in rat SNL and CCI models of neuropathic pain; attenuates cold allodynia in the CCI rat model at ≥3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
455.906726
产品形式:
A solid
纯度:
≥98%
CAS号:
1235560-28-7
分子式:
C20H20ClF2N3O3S
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