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折扣/货期| 货号：39515-10 mg | 规格：10 mg | 目录价：￥2774 |
| 货号：39515-25 mg | 规格：25 mg | 目录价：￥6579 |
| 货号：39515-5 mg | 规格：5 mg | 目录价：￥1461 |
| 货号：39515-50 mg | 规格：50 mg | 目录价：￥10961 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ABX-464
产品描述:
An HIV anti-replicative agent; induces aberrant splicing in HIV pre-mRNA expressed from host-integrated viral DNA and produces non-typical mRNA in primary PBMCs from HIV-infected patients without disrupting normal cellular mRNA splicing at 5 µM; increases the expression of miR-124 in both uninfected and HIV-infected PBMCs at 5 µM; reduces the replication of seven HIV-1 mutant strains by 71-99% in HIV-infected primary PBMCs; reduces HIV RNA levels and losses of CD4+, CD8+, and CD4+/CD8+ T cells in isolated peritoneal cells, as well as limits the extent of viral rebound, in a humanized mouse model of HIV infection at 20 mg/kg per day; prevents weight loss and decreased colon length, increases in colon lesion number and size, and the number of colon tissue macrophage infiltrates in a mouse model of DSS-induced ulcerative colitis at 50 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
338.711389
产品形式:
A solid
纯度:
≥95%
CAS号:
1258453-75-6
分子式:
C16H10ClF3N2O
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