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折扣/货期| 货号：10016-1 mg | 规格：1 mg | 目录价：￥965 |
| 货号：10016-10 mg | 规格：10 mg | 目录价：￥6713 |
| 货号：10016-5 mg | 规格：5 mg | 目录价：￥3605 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ac-YVAD-CHO
别名:
Caspase-1 Inhibitor I|L 709049|N-Ac-Tyr-Val-Ala-Asp-CHO
产品描述:
An inhibitor of caspase-1 (Ki = 0.76 nM); selective for caspase-1 over caspase-4, -5, -8, -9, and -10 (Kis = 163-970 nM), as well as over caspase-2, -3, -6, and -7 (Kis = >10,000 nM for all); inhibits activation of caspase-1 and IL-1β in a cell-free assay at 5 µM; reduces pancreatic levels of IL-18 and serum levels of IL-1β, as well as reduces pyroptosis of pancreatic cells, in a mouse model of cerulein-induced acute pancreatitis at 12.5 µmol/kg; increases susceptibility to lethal E. coli infection but prevents LPS-induced death in C3H-HeN mice at 5 and 10 mg/kg, respectively
保存温度:
-20
运输温度:
-20
预期分子量:
492.5
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
143313-51-3
分子式:
C23H32N4O8
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