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折扣/货期| 货号：29657-1 mg | 规格：1 mg | 目录价：￥536 |
| 货号：29657-10 mg | 规格：10 mg | 目录价：￥3296 |
| 货号：29657-25 mg | 规格：25 mg | 目录价：￥7517 |
| 货号：29657-5 mg | 规格：5 mg | 目录价：￥1769 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AC480
别名:
BMS-599626
产品描述:
A dual inhibitor of EGFR and HER2 (IC50s = 22 and 32 nM, respectively); selective for EGFR and HER2 over HER4 (IC50 = 190 nM) and a panel of 21 additional kinases (IC50s = >2,500 nM for all); inhibits proliferation in a panel of EGFR and/or HER2 signaling-dependent cancer cells (IC50s = 0.24-0.94 μM); reduces tumor growth in a Sal2 murine salivary gland tumor model, as well as GEO colon and KPL4 breast cancer mouse xenograft models in a dose-dependent manner; reduces tumor cell motility, intravasation, and EGF-induced invasion in an MTLn3E metastatic mammary adenocarcinoma mouse xenograft model at 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
530.553803
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
714971-09-2
分子式:
C27H27FN8O3
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