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折扣/货期| 货号：41522-10 mg | 规格：10 mg | 目录价：￥5976 |
| 货号：41522-25 mg | 规格：25 mg | 目录价：￥13266 |
| 货号：41522-5 mg | 规格：5 mg | 目录价：￥3323 |
| 货号：41522-50 mg | 规格：50 mg | 目录价：￥18251 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Acoramidis
别名:
AG-10
产品描述:
A TTR kinetic stabilizer; selectively binds to wild-type TTR and TTRV122I with negative cooperativity (Kd1s = 4.8 and 6.2 nM, respectively; Kd2s = 314 and 139 nM, respectively) over COX-1, COX-2, and the thyroid hormone nuclear receptor (IC50s = >10 µM for all); inhibits pH-induced amyloidogenesis of wild-type TTR and TTRV122I, indicating tetramer stabilization; stabilizes TTRV122I in serum isolated from patients with familial amyloid cardiomyopathy at 10 µM
保存温度:
-20
运输温度:
-20
预期分子量:
292.305563
产品形式:
A solid
纯度:
≥98%
CAS号:
1446711-81-4
分子式:
C15H17FN2O3
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