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折扣/货期| 货号：41536-10 mg | 规格：10 mg | 目录价：￥3323 |
| 货号：41536-25 mg | 规格：25 mg | 目录价：￥7370 |
| 货号：41536-5 mg | 规格：5 mg | 目录价：￥1849 |
| 货号：41536-50 mg | 规格：50 mg | 目录价：￥12904 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Acoramidis (hydrochloride)
别名:
AG-10
产品描述:
A TTR kinetic stabilizer; selectively binds to wild-type TTR and TTRV122I with negative cooperativity (Kd1s = 4.8 and 6.2 nM, respectively; Kd2s = 314 and 139 nM, respectively) over COX-1, COX-2, and the thyroid hormone nuclear receptor (IC50s = >10 µM for all); inhibits pH-induced amyloidogenesis of wild-type TTR and TTRV122I, indicating tetramer stabilization; stabilizes TTRV122I in serum isolated from patients with familial amyloid cardiomyopathy at 10 µM
保存温度:
-20
运输温度:
-20
预期分子量:
328.766203
产品形式:
A solid
纯度:
≥98%
CAS号:
2242751-53-5
分子式:
C15H17FN2O3• HCl
促销活动
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