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折扣/货期| 货号：26173-10 mg | 规格：10 mg | 目录价：￥2251 |
| 货号：26173-25 mg | 规格：25 mg | 目录价：￥4650 |
| 货号：26173-5 mg | 规格：5 mg | 目录价：￥1273 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ACY-241
别名:
Citarinostat
产品描述:
An HDAC6 inhibitor (IC50 = 2.6 nM); selective for HDAC6 over HDAC1-3, HDAC7, and HDAC9 (IC50s = 35, 45, 46, 7,300, and 137 nM, respectively), as well as HDAC4, HDAC5, and HDAC9 (IC50 = >20,000 nM for all); reduces proliferation of A2780, TOV-21G, and MDA-MB-231 cells at 3 µM and completely inhibits it and induces apoptosis at 10 µM; inhibits proliferation in MiaPaCa-2, TOV-21G, and T47D cells when used in combination with paclitaxel; reduces tumor growth in a MiaPaCa-2 mouse xenograft model at 50 mg/kg when used in combination with paclitaxel; reduces hepatorenal cystogenesis in a rat model of polycystic liver disease when used in combination with pasireotide
保存温度:
-20
运输温度:
-20
预期分子量:
468
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1316215-12-9
分子式:
C24H26ClN5O3
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