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折扣/货期| 货号：13655-1 g | 规格：1 g | 目录价：￥5668 |
| 货号：13655-100 mg | 规格：100 mg | 目录价：￥871 |
| 货号：13655-250 mg | 规格：250 mg | 目录价：￥1849 |
| 货号：13655-500 mg | 规格：500 mg | 目录价：￥3055 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Adapalene
别名:
CD 271
产品描述:
A synthetic retinoid; an agonist of RARs (Kds = 1,100, 34, and 130 nM for RARα, RARβ, and RARγ, respectively); inhibits growth and differentiation of sebocytes in primary rat preputial cell culture; completely inhibits the activity of soybean 15-LOX in an enzyme assay at 10 μM; inhibits the 5- and 15-LOX pathways in human blood PMNs at 10 μM; reduces the protein levels of TLR2 and IL-10 in skin explants isolated from patients with acne as well as healthy controls; increases the expression of CD1d in acne skin explants while decreasing it in control explants; inhibits inflammation in rodent models of ear edema induced by arachidonic acid and carrageenan-induced paw edema; induces apoptosis and inhibits proliferation of CC-531, HT-29, and LoVo colon cancer cells at 100 μM; reduces tumor growth in a DLD-1 colon cancer nude mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
412.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
106685-40-9
分子式:
C28H28O3
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